Exchange Server Database = C:\Program Files\Exchsrvr\
Exchange MTA files = C:\Program Files\Exchsrvr\Mtadata
Exchange Message tracking log files = C:\Program Files\Exchsrvr\<servername>.log
Exchange SMTP Mailroot = C:\Program Files\Exchsrvr\Mailroot
Exchange working files = C:\Program Files\Exchsrvr\Mdbdata
Site Replication = C:\Program Files\Exchsrvr\srsdata  & C:\Program Files\Exchsrvr\Conndata

(Note that some of these folders may have been moved to an alternative volume for performance purposes)

IIS System Files = C:\WINDOWS\system32\inetsrv
IIS Compression Folder = C:\WINDOWS\IIS Temporary Compressed Files

Active Directory database files = C:\WINDOWS\NTDS
SYSVOL C:\WINDOWS\SYSVOL
NTFRS Database Files = C:\WINDOWS\ntfrs

Temporary SharePoint space = C:\windows\temp\Frontpagetempdir

Removable Storage Database (used by SBS Backup) = C:\Windows\System32\ntmsdata
SBS POP3 connector Failed Mail = C:\Program Files\Microsoft Windows Small Business Server\Networking\POP3\Failed Mail
SBS POP3 connector Incoming Mail = C:\Program Files\Microsoft Windows Small Business Server\Networking\POP3\Incoming Mail
Windows Update Store = C:\WINDOWS\SoftwareDistribution\DataStore

DHCP Database Store = C:\WINDOWS\system32\dhcp
WINS Database Store = C:\WINDOWS\system32\wins

License Logging = C:\WINDOWS\system32\lls\

Desktop Folder Exclusions

These folders need to be excluded in the desktops and notebooks clients.

Windows Update Store = C:\WINDOWS\SoftwareDistribution\DataStore